Directional selection, not the direction of selection, affects telomere length and copy number at ribosomal RNA loci.

ABSTRACT: Many fisheries exert directional selection on traits such as body size and growth rate. Whether directional selection impacts regions of the genome associated with traits related to growth is unknown. To address this issue, we characterised copy number variation in three regions of the genome associated with cell division, (1) telomeric DNA, (2) loci transcribed as ribosomal RNA (rDNA), and (3) mitochondrial DNA (mtDNA), in three selection lines of zebrafish reared at three temperatures (22 °C, 28 °C, and 34 °C). Selection lines differed in (1) the direction of selection (two lines experienced directional selection for large or small body size) and (2) whether they experienced any directional selection itself. Lines that had experienced directional selection were smaller, had lower growth

SUBMITTER: Sadler DE 

PROVIDER: S-EPMC11130246 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature