Unveiling the anti-echinococcal efficacy of amide-based compounds: An in-silico and in-vitro study.

ABSTRACT: Cystic echinococcosis (CE) is a significant global public health concern, particularly in regions where livestock rearing is prevalent. Despite its impact on morbidity and mortality, CE has received insufficient attention compared to other neglected tropical diseases. The complexities in CE management arise from challenges in early detection, effective treatment, and parasite eradication. The present study addresses this gap by exploring innovative therapeutic approaches using amide-based compounds. In recent years, computational approaches and in-vitro studies have become prominent in neglected tropical disease drug discovery. Leveraging insights from previous studies on amide-based compounds with anti-parasitic potential, this study systematically designed, synthesized, and charac

SUBMITTER: Chauhan V 

PROVIDER: S-EPMC11130662 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature