The Effectiveness of Paired Associative Stimulation on Motor Recovery after Stroke: A Scoping Review.

ABSTRACT: Paired associative stimulation (PAS) is a non-invasive brain stimulation technique combining transcranial magnetic stimulation and peripheral nerve stimulation. PAS allows connections between cortical areas and peripheral nerves (C/P PAS) or between cortical regions (C/C PAS) to be strengthened or weakened by spike-timing-dependent neural plasticity mechanisms. Since PAS modulates both neurophysiological features and motor performance, there is growing interest in its application in neurorehabilitation. We aimed to synthesize evidence on the motor rehabilitation role of PAS in stroke patients. We performed a literature search following the PRISMA Extension for Scoping Reviews Framework. Eight studies were included: one investigated C/C PAS between the cerebellum and the affected primary mo

SUBMITTER: Baroni A 

PROVIDER: S-EPMC11130975 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature