Reducing overdose deaths among persons with opioid use disorder in connecticut.

ABSTRACT:

Background

People in Connecticut are now more likely to die of a drug-related overdose than a traffic accident. While Connecticut has had some success in slowing the rise in overdose death rates, substantial additional progress is necessary.

Methods

We developed, verified, and calibrated a mechanistic simulation of alternative overdose prevention policy options, including scaling up naloxone (NLX) distribution in the community and medications for opioid use disorder (OUD) among people who are incarcerated (MOUD-INC) and in the community (MOUD-COM) in a simulated cohort of people with OUD in Connecticut. We estimated how maximally scaling up each option individually and in combinations would impact 5-year overdose deaths, life-years, and quality-adjusted life-years. All costs

SUBMITTER: Scheidell JD 

PROVIDER: S-EPMC11131266 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature