Novel paradigm enables accurate monthly gestational screening to prevent congenital toxoplasmosis and more.

ABSTRACT:

Background

Congenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, and substantial costs worldwide.

Objectives

We asked whether high performance of an Immunochromatographic-test (ICT) could enable accurate, rapid diagnosis/treatment, establishing new, improved care-paradigms at point-of-care and clinical laboratory.

Methods

Data were obtained in 12 studies/analyses addressing: 1-feasibility/efficacy; 2-false-positives; 3-acceptability; 4-pink/black-line/all studies; 5-time/cost; 6-Quick-Information/Limit-of-detection; 7, 8-acute;-chronic; 9-epidemiology; 10-ADBio; 11,12-Commentary/Cases/Chronology.

Findings

ICT was compared with gold-standard or predicate-tests. Overall,

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC11132520 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature