Clinical and computational development of a patient-calibrated ICGFA bowel transection recommender.

ABSTRACT:

Introduction

Intraoperative indocyanine green fluorescence angiography (ICGFA) aims to reduce colorectal anastomotic complications. However, signal interpretation is inconsistent and confounded by patient physiology and system behaviours. Here, we demonstrate a proof of concept of a novel clinical and computational method for patient calibrated quantitative ICGFA (QICGFA) bowel transection recommendation.

Methods

Patients undergoing elective colorectal resection had colonic ICGFA both immediately after operative commencement prior to any dissection and again, as usual, just before anastomotic construction. Video recordings of both ICGFA acquisitions were blindly quantified post hoc across selected colonic regions of interest (ROIs) using tracking-quantification software and

SUBMITTER: Dalli J 

PROVIDER: S-EPMC11133155 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature