Fully-automated CT derived body composition analysis reveals sarcopenia in functioning adrenocortical carcinomas.

ABSTRACT: Determination of body composition (the relative distribution of fat, muscle, and bone) has been used effectively to assess the risk of progression and overall clinical outcomes in different malignancies. Sarcopenia (loss of muscle mass) is especially associated with poor clinical outcomes in cancer. However, estimation of muscle mass through CT scan has been a cumbersome, manually intensive process requiring accurate contouring through dedicated personnel hours. Recently, fully automated technologies that can determine body composition in minutes have been developed and shown to be highly accurate in determining muscle, bone, and fat mass. We employed a fully automated technology, and analyzed images from a publicly available cancer imaging archive dataset (TCIA) and a tertiary academic ce

SUBMITTER: Santhanam P 

PROVIDER: S-EPMC11133428 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature