Dietary supplement for mood symptoms in early postpartum: a double-blind randomized placebo controlled trial.

ABSTRACT:

Background

Postpartum blues (PPB) is a frequent syndrome of sad mood, crying spells, anxiety, restlessness, reduced appetite, and irritability, typically peaking day 5 postpartum. When severe, it greatly increases risk for later postpartum depression. This trial compared a dietary supplement to placebo on PPB severity. The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB.

Methods

Participants recruited by advertisement from the Toronto region completed procedures at CAMH, Canada and/or participants' homes. Oral supplement or identical appearing relatively inert placebo were administered in randomised, double-blind fashion. Supplement was blueberry juice and extract given four times between nighttime day 3

SUBMITTER: Meyer JH 

PROVIDER: S-EPMC11133796 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature