Volumetric hyperthermia delivery using the ExAblate Body MR-guided focused ultrasound system.

ABSTRACT:

Objectives

To investigate image-guided volumetric hyperthermia strategies using the ExAblate Body MR-guided focused ultrasound ablation system, involving mechanical transducer movement and sector-vortex beamforming.

Materials and methods

Acoustic and thermal simulations were performed to investigate volumetric hyperthermia using mechanical transducer movement combined with sector-vortex beamforming, specifically for the ExAblate Body transducer. The system control in the ExAblate Body system was modified to achieve fast transducer movement and MR thermometry-based hyperthermia control, mechanical transducer movements and electronic sector-vortex beamforming were combined to optimize hyperthermia delivery. The experimental validation was performed using a tissue-mimicking pha

SUBMITTER: Kim K 

PROVIDER: S-EPMC11135290 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature