Determining the library size for the optimal output plan in the RapidPlan knowledge-based planning system using multicriteria optimization.

ABSTRACT:

Objectives

The aim of this study was to determine the number of trade-off explored (TO) library plans required for building a RapidPlan (RP) library that would generate the optimal clinical treatment plan.

Methods

We developed 2 RP models, 1 each for the 2 clinical sites, head and neck (HN) and cervix. The models were created using 100 plans and were validated using 70 plans (VP) for each site respectively. Each of the 2 libraries comprising 100 TO plans was divided into 5 different subsets of library plans comprising 20, 40, 60, 80, and 100 plans, leading to 5 different RP models for each site. For every validation patient, a TO plan (TO_VP) was created. For every patient, 5 RP plans were automatically generated using RP models. The dosimetric parameters of the 6 plans (TO_

SUBMITTER: Biswal SS 

PROVIDER: S-EPMC11135798 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature