Clostridium difficile infection after stoma reversal surgery: a systematic review and meta-analysis of the literature.

ABSTRACT:

Background

Clostridium difficile infection (CDI) has been described in the early post-operative phase after stoma reversal. This systematic review aimed to describe the incidence of CDI after stoma reversal and to identify pre-operative variables correlated with an increased risk of infection.

Methods

A systematic review of the literature was conducted according to the PRISMA guidelines in March 2024. Manuscripts were included if reported at least one patient with CDI-associated diarrhoea following stoma reversal (colostomy/ileostomy). The primary outcome of interest was the incidence of CDI; the secondary outcome was the comparison of clinical variables (age, sex, time to stoma reversal, neo-adjuvant and adjuvant therapies after index colorectal procedure) in CDI-positive v

SUBMITTER: Tirelli F 

PROVIDER: S-EPMC11136761 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature