Impact of prior antihypertensive treatment on COVID-19 outcomes, by active ingredient.

ABSTRACT:

Objectives

To assess the impact of prior chronic treatment with angiotensin-converting enzyme inhibitors (ACEIs)/ angiotensin-receptor blockers (ARBs), both as a group and by active ingredient, on severity (risk of hospitalization and mortality), progression of and susceptibility to COVID-19.

Methods

We conducted a multiple population-based case-control study in Galicia (north-west Spain). The study data were sourced from medical, administrative and clinical databases. We assessed: (1) risk of hospitalization, by selecting all patients hospitalized due to COVID-19 with PCR + as cases, and a random sample of subjects without a PCR + as controls; (2) COVID-19 mortality risk; (3) risk of disease progression; and (4) susceptibility to SARS-CoV-2, considering all patients with PC

SUBMITTER: Garcia-Alvarez RM 

PROVIDER: S-EPMC11136854 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature