Respiratory muscle strength can improve the prognostic assessment in COPD.

ABSTRACT: Impaired lung function, respiratory muscle weakness and exercise intolerance are present in COPD and contribute to poor prognosis. However, the contribution of the combination of these manifestations to define prognosis in COPD is still unknown. This study aimed to define cut-off points for both inspiratory and expiratory muscle strength (MIP and MEP, respectively) for mortality prediction over 42-months in patients with COPD, and to investigate its combination with other noninvasive established prognostic measures (FEV₁, V̇O_2peak and 6MWD) to improve risk identification. Patients with COPD performed pulmonary function, respiratory muscle strength, six-minute walk and cardiopulmonary exercise tests, and were followed over 42 months to analyze all-cause mortality. A to

SUBMITTER: Silva RN 

PROVIDER: S-EPMC11137089 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature