A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer.

ABSTRACT: Breast cancer is a multifaceted disease and a leading cause of cancer morbidity and mortality in females across the globe. In 2020 alone, 2.3 million women were diagnosed and 685,000 died of breast cancer worldwide. With the number of diagnoses projected to increase to 3 million per year by 2040 it is essential that new methods of detection and disease stratification are sought to decrease this global cancer burden. Although significant improvements have been made in breast cancer diagnosis and treatment, the prognosis of breast cancer remains poor in some patient groups (i.e. triple negative breast cancer), necessitating research into better patient stratification, diagnosis and drug discovery. The UK Biobank, a comprehensive biomedical and epidemiological database with a wide variety of

SUBMITTER: van den Driest L 

PROVIDER: S-EPMC11137368 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature