Comparative analysis of two-hour creatinine clearance and the C-G formula for renal function assessment in critically ill patients.

ABSTRACT:

Objective and rationale

To investigate if the 2-h creatinine clearance (Ccr₂) provides a more precise and timely assessment of renal function in critically ill patients compared to the Cockcroft-Gault formula (Cr_C-G).

Materials and methods

This cohort study incorporated 74 patients who were hospitalized for more than 48 h in the Intensive Care Unit over 6 months. A 24-h urine collection protocol was observed, and concurrently, 316 2-h urine specimens were obtained. Then calculated and analyzed the correlation and consistency between Ccr₂, Cr_C-G, and 24-h creatinine clearance (Ccr₂₄) values. The rates of change in Ccr₂(ΔCcr₂) and Cr_C-G(ΔCr_C-G) were compared over two consecutive

SUBMITTER: Liu C 

PROVIDER: S-EPMC11137534 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature