Iron-Catalyzed C-H Oxygenation Using Perchlorate Enabled by Secondary Sphere Hydrogen Bonds.

ABSTRACT: Perchlorate (ClO₄^-) is a groundwater pollutant that is challenging to remediate. We report a strategy to use Fe(II) tris(2-pyridylmethyl)amine (TPA) complexes featuring appended aniline hydrogen bonds (H-bonds) to promote ClO₄^- reduction. These complexes facilitate oxygen atom transfer from ClO₄^- to PPh₃ and C-H oxygenation reactions of organic substrates. Catalytic reactions using 15 mol % afforded excellent yields for oxygenation of anthracene and cyclic alkyl aromatics, and this methodology tolerates aryl halides as well as heterocycles containing either O, S, or N.

SUBMITTER: Sarkar W 

PROVIDER: S-EPMC11137739 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature