Incidence rate of occult lymph node metastasis in clinical T_1-2N₀M₀ small cell lung cancer patients and radiomic prediction based on contrast-enhanced CT imaging: a multicenter study : Original research.

ABSTRACT:

Background

This study aimed to explore the incidence of occult lymph node metastasis (OLM) in clinical T_1 - 2N₀M₀ (cT_1 - 2N₀M₀) small cell lung cancer (SCLC) patients and develop machine learning prediction models using preoperative intratumoral and peritumoral contrast-enhanced CT-based radiomic data.

Methods

By conducting a retrospective analysis involving 242 eligible patients from 4 centeres, we determined the incidence of OLM in cT_1 - 2N₀M₀ SCLC patients. For each lesion, two ROIs were defined using the gross tumour volume (GTV) and peritumoral volume 15 mm around the tumour (PTV). By extracting a comprehensive set of 1595 enhanced CT-based radiomic features individually f

SUBMITTER: Jiang X 

PROVIDER: S-EPMC11138070 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature