Current US prevalence of myocardial injury patterns and clinical outcomes among hospitalised patients with familial hypercholesterolaemia: insight from the National Inpatient Sample-a retrospective cohort study.

ABSTRACT:

Background

Familial hypercholesterolaemia (FH) increases propensity for premature atherosclerotic disease. Knowledge of inpatient outcomes among patients with FH admitted with acute myocardial injury (AMI) is limited.

Objectives

Our study aimed to identify myocardial injury types, including type 1 myocardial infarction (MI), type 2 MI and takotsubo cardiomyopathy, assess lesion severity and study adverse short-term inpatient outcomes among patients with FH admitted with AMI.

Setting

Our study retrospectively queried the US National Inpatient Sample from 2018 to 2020.

Population

Adults admitted with AMI and dichotomised based on the presence of FH.

Study outcomes

We evaluated myocardial injury types and complexity of coronary revascularisation. Primary ou

SUBMITTER: Kumi D 

PROVIDER: S-EPMC11138297 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature