Associations between stimulant use and return to illicit opioid use following initiation onto medication for opioid use disorder.

ABSTRACT:

Aim

The aim of this study was to estimate how ongoing stimulant use affects return to illicit opioid use after initiation onto medication for opioid use disorder (MOUD).

Design

This was a secondary analysis of pooled data from two clinical trials comparing buprenorphine (BUP-NX) and extended-release naltrexone (XR-NTX).

Setting

Thirteen opioid treatment programs and HIV clinics across 10 states in the United States from 2014 to 2019 took part in this study.

Participants

A total of 528 participants who initiated MOUD as part of trial participation were included. Nearly half (49%) were between 30 and 49 years of age, 69% were male and 66% were non-Hispanic White.

Measurements

The primary outcome was first self-reported day of non-prescribed opioid use foll

SUBMITTER: Foot C 

PROVIDER: S-EPMC11139042 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature