Population attributable fractions of modifiable risk factors for dementia: a systematic review and meta-analysis.

ABSTRACT:

Background

More than 57 million people have dementia worldwide. Evidence indicates a change in dementia prevalence and incidence in high-income countries, which is likely to be due to improved life-course population health. Identifying key modifiable risk factors for dementia is essential for informing risk reduction and prevention strategies. We therefore aimed to estimate the population attributable fraction (PAF) for dementia associated with modifiable risk factors.

Methods

In this systematic review and meta-analysis, we searched Embase, MEDLINE, and PsycINFO, via Ovid, from database inception up to June 29, 2023, for population-derived or community-based studies and reviews reporting a PAF value for one or more modifiable risk factor for later-life dementia (prevalent or

SUBMITTER: Stephan BCM 

PROVIDER: S-EPMC11139659 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature