Severity and progression of structural hand OA is not associated with progression of structural knee OA: The IMI-APPROACH cohort.

ABSTRACT:

Objective

To investigate whether structural hand OA or its progression is associated with structural knee OA progression after two years in a population with symptomatic knee OA.

Methods

We used baseline and two-year follow-up data from the IMI-APPROACH cohort. Symptomatic hand and knee OA were defined using ACR criteria. Radiographs of hands and knees were scored semi-quantitatively for osteophytes and joint space narrowing (JSN) following the OARSI atlas, and Kellgren-Lawrence (KL) scale. Knee images were also scored quantitatively with the Knee Image Digital Analysis (KIDA). Progression was defined as change above the minimal detectable change on patient level, except for KIDA (most affected knee compartment level). With logistic regression analyses the severity or progre

SUBMITTER: Terpstra SES 

PROVIDER: S-EPMC11141256 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature