Live birth outcomes following single-step blastocyst warming technique - optimizing efficiency without impacting live birth rates.

ABSTRACT:

Purpose

To evaluate the impact of a single-step (SS) warming versus standard warming (SW) protocol on the survival/expansion of vitrified blastocysts and their clinical outcomes post-frozen embryo transfer (FET).

Methods

Retrospective analysis was performed on 200 vitrified/warmed research blastocysts equally divided amongst two thawing protocols utilizing the Fujifilm Warming NX kits (Fujifilm, CA). SW utilized the standard 14-minute manufacturer's guidelines. SS protocol required only a one-minute immersion in thaw solution (TS) before the embryos were transferred to culture media. A time-interrupted study was performed evaluating 752 FETs (SW: 376 FETs, SS 376 FETs) between April 2021-December 2022 at a single academic fertility clinic in Boston, Massachusetts. Embryologi

SUBMITTER: Jiang VS 

PROVIDER: S-EPMC11143112 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature