Human metaphase II oocytes with narrow perivitelline space have poor fertilization, developmental, and pregnancy potentials.

ABSTRACT:

Purpose

To analyze the fertilization, developmental, and pregnancy potentials in oocytes with narrow perivitelline space.

Methods

Perivitelline space (PVS) of oocytes was evaluated at the time of ICSI, and those without sufficient PVS were judged as oocytes with narrow PVS (NPVS oocytes), and those with sufficient PVS formation were judged as oocytes with non-narrow PVS (non-NPVS oocytes). The analysis included 634 NPVS oocytes from 278 cycles and 12,121 non-NPVS oocytes from 1698 cycles. The fertilization and developmental potentials of NPVS and non-NPVS oocytes were compared by calculating odds ratios using a mixed-effects logistic regression model. We also compared the embryo transfer outcomes of those used for single vitrified-warmed blastocyst transfer after developing

SUBMITTER: Shioya M 

PROVIDER: S-EPMC11143139 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature