Mortality After Major Cardiovascular Events in Survivors of Childhood Cancer.

ABSTRACT:

Background

Adult survivors of childhood cancer are at risk for cardiovascular events.

Objectives

In this study, we sought to determine the risk for mortality after a major cardiovascular event among childhood cancer survivors compared with noncancer populations.

Methods

All-cause and cardiovascular cause-specific mortality risks after heart failure (HF), coronary artery disease (CAD), or stroke were compared among survivors and siblings in the Childhood Cancer Survivor Study (CCSS) and participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study. Cox proportional hazard regression models were used to estimate HRs and 95% CIs between groups, adjusted for demographic and clinical factors.

Results

Among 25,658 childhood cancer survivors (med

SUBMITTER: Bottinor W 

PROVIDER: S-EPMC11144450 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature