Omicron neutralization character in patients with breast cancer and liver cancer after the nationwide omicron outbreak.

ABSTRACT:

Background

The surge in omicron variants has caused nationwide breakthrough infections in mainland China since the December 2022. In this study, we report the neutralization profiles of serum samples from the patients with breast cancer and the patients with liver cancer who had contracted subvariant breakthrough infections.

Methods

In this real-world study, we enrolled 143 COVID-19-vaccinated (81 and 62 patients with breast and liver cancers) and 105 unvaccinated patients with cancer (58 and 47 patients with breast and liver cancers) after omicron infection. Anti-spike receptor binding domain (RBD) IgGs and 50% pseudovirus neutralization titer (pVNT₅₀) for the preceding (wild type), circulating omicron (BA.4-BA.5, and BF.7), and new subvariants (XBB.1.5) were com

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11144947 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature