Environmental activity-based protein profiling for function-driven enzyme discovery from natural communities.

ABSTRACT:

Background

Microbial communities are important drivers of global biogeochemical cycles, xenobiotic detoxification, as well as organic matter decomposition. Their major metabolic role in ecosystem functioning is ensured by a unique set of enzymes, providing a tremendous yet mostly hidden enzymatic potential. Exploring this enzymatic repertoire is therefore not only relevant for a better understanding of how microorganisms function in their natural environment, and thus for ecological research, but further turns microbial communities, in particular from extreme habitats, into a valuable resource for the discovery of novel enzymes with potential applications in biotechnology. Different strategies for their uncovering such as bioprospecting, which relies mainly on metagenomic approache

SUBMITTER: Ninck S 

PROVIDER: S-EPMC11145796 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature