DNA mutations of the cat: the good, the bad and the ugly.

ABSTRACT:

Practical relevance

The health of the cat is a complex interaction between its environment (nurture) and its genetics (nature). Over 70 genetic mutations (variants) have been defined in the cat, many involving diseases, structural abnormalities and clinically relevant health concerns. As more of the cat's genome is deciphered, less commonly will the term 'idiopathic' be used regarding the diagnosis of diseases and unique health conditions. State-of-the-art health care will include DNA profiling of the individual cat, and perhaps its tumor, to establish the best treatment approaches. Genetic testing and eventually whole genome sequencing should become routine diagnostics for feline health care.

Global importance

Cat breeds have disseminated around the world. Thus, practitione

SUBMITTER: Lyons LA 

PROVIDER: S-EPMC11148888 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature