Quantifying variations associated with dental caries reveals disparity in effect allele frequencies across diverse populations.

ABSTRACT:

Background

Dental caries (DC) is a multifaceted oral condition influenced by genetic and environmental factors. Recent advancements in genotyping and sequencing technologies, such as Genome-Wide Association Studies (GWAS) have helped researchers to identify numerous genetic variants associated with DC, but their prevalence and significance across diverse global populations remain poorly understood as most of the studies were conducted in European populations, and very few were conducted in Asians specifically in Indians.

Aim

This study aimed to evaluate the genetic affinity of effect alleles associated with DC to understand the genetic relationship between global populations with respect to the Indian context.

Methodology

This present study used an empirical approach

SUBMITTER: Sandhu S 

PROVIDER: S-EPMC11149341 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature