Hemoglobin Concentration Impacts Viscoelastic Hemostatic Assays in ICU Admitted Patients.

ABSTRACT:

Objectives

Low hemoglobin concentration impairs clinical hemostasis across several diseases. It is unclear whether hemoglobin impacts laboratory functional coagulation assessments. We evaluated the relationship of hemoglobin concentration on viscoelastic hemostatic assays in intracerebral hemorrhage (ICH) and perioperative patients admitted to an ICU.

Design

Observational cohort study and separate in vitro laboratory study.

Setting

Multicenter tertiary referral ICUs.

Patients

Two acute ICH cohorts receiving distinct testing modalities: rotational thromboelastometry (ROTEM) and thromboelastography (TEG), and a third surgical ICU cohort receiving ROTEM were evaluated to assess the generalizability of findings across disease processes and testing platforms. A sepa

SUBMITTER: Roh DJ 

PROVIDER: S-EPMC11149397 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature