Exploring the potential mechanisms of Danshen against COVID-19 via network pharmacology analysis and molecular docking.

ABSTRACT: Danshen, a prominent herb in traditional Chinese medicine (TCM), is known for its potential to enhance physiological functions such as blood circulation, immune response, and resolve blood stasis. Despite the effectiveness of COVID-19 vaccination efforts, some individuals still face severe complications post-infection, including pulmonary fibrosis, myocarditis arrhythmias and stroke. This study employs a network pharmacology and molecular docking approach to investigate the potential mechanisms underlying the therapeutic effects of candidate components and targets from Danshen in the treatment of complications in COVID-19. Candidate components and targets from Danshen were extracted from the TCMSP Database, while COVID-19-related targets were obtained from Genecards. Venn diagram analysis

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC11150561 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature