Comprehensive expression, prognostic and validation analysis of necroptosis-related lncRNAs in esophageal cancer.

ABSTRACT:

Background

Previous studies have shown that necroptosis-related long noncoding RNA (lncRNA) risk models can be used to predict prognosis and immune infiltration in patients with esophageal cancer. However, further analysis of the regulatory mechanisms of necroptosis-related lncRNAs used in risk models remains to be conducted. The purpose of the present study was to identify valuable necroptosis-related lncRNAs in esophageal cancer and to verify their molecular and cellular functions.

Methods

Esophageal cancer data were downloaded from The Cancer Genome Atlas (TCGA). The expression of eight genes (LINC00299, AC090912.2, AC244197.2, AL158166.1, AC079684.1, AP003696.1, AC079684.1 and AP003696.1) in the necroptosis-related lncRNA risk model, their relationships with clinicopatho

SUBMITTER: Duan X 

PROVIDER: S-EPMC11152745 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature