Long-term variability of retinal nerve fibre layer thickness measurement in patients with glaucoma of African and European descents.

ABSTRACT:

Background

To examine long-term retinal nerve fibre layer thickness (RNFLT) variability and associated clinical factors in African (AD) and European descent (ED) individuals with glaucoma.

Methods

This retrospective cohort study included glaucoma eyes of AD and ED from Diagnostic Innovations in Glaucoma Study/The African Descent and Glaucoma Evaluation Study with ≥4 visits/2 years of follow-up. We calculated optic nerve head RNFLT variability per-examination/visit as the absolute error of its residuals across follow-up. Full, baseline and parsimonious linear-mixed models were fit to evaluate the effects of clinical factors (demographics and ocular characteristics, prior/intervening glaucoma surgeries and cataract extraction (CE), RNFLT thinning rate, scan quality, visit/test

SUBMITTER: Wu JH 

PROVIDER: S-EPMC11153332 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature