Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil.

ABSTRACT: Glucose-6 phosphate dehydrogenase deficiency (G6PDd) was suggested as a risk factor for severe disease in patients with COVID-19. We evaluated clinical outcomes and glucose-6 phosphate dehydrogenase (G6PD) activity during and after illness in patients with COVID-19. This prospective cohort study included adult participants (≥ 18 years old) who had clinical and/or radiological COVID-19 findings or positive reverse transcription-polymerase chain reaction results. Epidemiological and clinical data were extracted from electronic medical records. Glucose-6 phosphate dehydrogenase activity was measured using SD Biosensor STANDARD G6PD® equipment on admission and 1 year after discharge. Samples were genotyped for the three most common single nucleotide polymorphisms for G6PDd in the Brazilian Ama

SUBMITTER: de Almeida Rodrigues MG 

PROVIDER: S-EPMC11154054 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature