Mortality and Morbidity in Adults With Rheumatic Heart Disease.

ABSTRACT:

Importance

Rheumatic heart disease (RHD) remains a public health issue in low- and middle-income countries (LMICs). However, there are few large studies enrolling individuals from multiple endemic countries.

Objective

To assess the risk and predictors of major patient-important clinical outcomes in patients with clinical RHD.

Design, setting, and participants

Multicenter, hospital-based, prospective observational study including 138 sites in 24 RHD-endemic LMICs.

Main outcomes and measures

The primary outcome was all-cause mortality. Secondary outcomes were cause-specific mortality, heart failure (HF) hospitalization, stroke, recurrent rheumatic fever, and infective endocarditis. This study analyzed event rates by World Bank country income groups and determined

SUBMITTER: Karthikeyan G 

PROVIDER: S-EPMC11154374 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature