Myo-inositol in the Dorsal Anterior Cingulate Cortex is Associated with Anxiety-to-Eat in Anorexia Nervosa.

ABSTRACT: Anorexia nervosa (AN) is a mental and behavioral health condition characterized by an intense fear of body weight or fat gain, restriction of food intake resulting in low body weight, and distorted body image. Substantial research has focused on general anxiety in AN, but less is known about eating-related anxiety and its underlying neurobiological mechanisms. We sought to characterize anxiety-to-eat in AN and to examine neurometabolite levels in the dorsal anterior cingulate cortex (dACC), a brain region putatively involved in modulating anxiety-related responses, using edited magnetic resonance spectroscopy. Sixteen women hospitalized with AN and 16 women of healthy weight without a lifetime history of an eating disorder (healthy controls; HC) completed a computer-based behavioral task a

SUBMITTER: Song Y 

PROVIDER: S-EPMC11160692 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature