Time-resolved coupling between connectome harmonics and subjective experience under the psychedelic DMT.

ABSTRACT: Exploring the intricate relationship between brain's structure and function, and how this affects subjective experience is a fundamental pursuit in neuroscience. Psychedelic substances offer a unique insight into the influences of specific neurotransmitter systems on perception, cognition and consciousness. Specifically, their impact on brain function propagates across the structural connectome - a network of white matter pathways linking different regions. To comprehensively grasp the effects of psychedelic compounds on brain function, we used a theoretically rigorous framework known as connectome harmonic decomposition. This framework provides a robust method to characterize how brain function intricately depends on the organized network structure of the human connectome. We show that th

SUBMITTER: Vohryzek J 

PROVIDER: S-EPMC11160714 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature