Neuropsychological and social predictors of participation in a deep brain stimulation study of Parkinson's disease and dystonia.

ABSTRACT:

Objectives

Participation is essential to DBS research, yet circumstances that affect diverse participation remain unclear. Here we evaluate factors impacting participation in an adaptive DBS study of Parkinson's disease (PD) and dystonia.

Methods

Twenty participants were implanted with a sensing-enabled DBS device (Medtronic Summit RC+S) that allows neural data streaming in naturalistic settings and encouraged to stream as much as possible for the first five months after surgery. Using standardized baseline data obtained through neuropsychological evaluation, we compared neuropsychological and social variables to streaming hours.

Results

Marital status and irritability significantly impacted streaming hours (estimate=136.7, bootstrapped ( ^b ) CI</

SUBMITTER: Hahn A 

PROVIDER: S-EPMC11160823 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature