Morphometric Analysis of Spina Bifida after Fetal Repair Shows New Subtypes with Associated Outcomes.

ABSTRACT:

Importance

The binary classification of spina bifida lesions as myelomeningocele (with sac) or myeloschisis (without sac) belies a spectrum of morphologies, which have not been correlated to clinical characteristics and outcomes.

Objective

To characterize spina bifida lesion types and correlate them with preoperative presentation and postoperative outcomes.

Design

Secondary analysis of images and videos obtained during fetoscopic spina bifida repair surgery from 2020-2023.

Setting

Fetal surgery was performed at a quaternary care center.

Participants

A prospective cohort of patients referred for fetal spina bifida underwent fetoscopic repair under an FDA-approved protocol. Of 60 lesions repaired, 57 had available images and were included in the analysis.<

SUBMITTER: Mann LK 

PROVIDER: S-EPMC11160825 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature