A complex metabolic network and its biomarkers regulate laccase production in white-rot fungus Cerrena unicolor 87613.

ABSTRACT:

Background

White-rot fungi are known to naturally produce high quantities of laccase, which exhibit commendable stability and catalytic efficiency. However, their laccase production does not meet the demands for industrial-scale applications. To address this limitation, it is crucial to optimize the conditions for laccase production. However, the regulatory mechanisms underlying different conditions remain unclear. This knowledge gap hinders the cost-effective application of laccases.

Results

In this study, we utilized transcriptomic and metabolomic data to investigate a promising laccase producer, Cerrena unicolor 87613, cultivated with fructose as the carbon source. Our comprehensive analysis of differentially expressed genes (DEGs) and differentially abundant metabolites

SUBMITTER: Zhang LB 

PROVIDER: S-EPMC11162070 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature