Transcranial focused ultrasound to V5 enhances human visual motion brain-computer interface by modulating feature-based attention.

ABSTRACT: A brain-computer interface (BCI) enables users to control devices with their minds. Despite advancements, non-invasive BCIs still exhibit high error rates, prompting investigation into the potential reduction through concurrent targeted neuromodulation. Transcranial focused ultrasound (tFUS) is an emerging non-invasive neuromodulation technology with high spatiotemporal precision. This study examines whether tFUS neuromodulation can improve BCI outcomes, and explores the underlying mechanism of action using high-density electroencephalography (EEG) source imaging (ESI). As a result, V5-targeted tFUS significantly reduced the error in a BCI speller task. Source analyses revealed a significantly increase in theta and alpha activities in the tFUS condition at both V5 and downstream in the dor

SUBMITTER: Kosnoff J 

PROVIDER: S-EPMC11167030 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature