Sleep apnea, hypoxia, and late-onset epilepsy: the Atherosclerosis Risk in Communities study.

ABSTRACT:

Study objective

Sleep apnea is associated with unexplained epilepsy in older adults in small studies. We sought to determine the relationship between sleep apnea and additional sleep characteristics and late-onset epilepsy (LOE), adjusting for comorbidities, using data from the large, prospective Atherosclerosis Risk in Communities (ARIC) Study cohort.

Methods

We used Medicare claims to identify cases of LOE in ARIC participants. We used polysomnography data from 1309 ARIC participants who also participated in the Sleep Heart Health Study in 1995-1998, and demographic and comorbidity data from ARIC. Later risk of LOE was evaluated using survival analysis with a competing risk of death. We also used survival analysis in 2672 ARIC participants to identify the association betwe

SUBMITTER: Carosella CM 

PROVIDER: S-EPMC11168763 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature