Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study.

ABSTRACT: Environmental exposure to heavy metals and metalloids, originating from sources such as mining and manufacturing activities, has been linked to adverse renal effects. This cross-sectional study assessed children's exposure to these elements and its association with urinary kidney injury molecule-1 (KIM-1). We analyzed data from 99 school-aged children residing in nine localities within the state of Colima, Mexico, during the latter half of 2023. Levels of 23 metals/metalloids and urinary KIM-1 were measured using inductively coupled plasma mass spectrometry (ICP-MS) and enzyme-linked immunosorbent assay, respectively. Detectable levels of these contaminants were found in over 91% of participants, with varied exposure profiles observed across locations ( p = 0.019). After adjusting for conf

SUBMITTER: Mendoza-Cano O 

PROVIDER: S-EPMC11169506 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature