Trends in urine lead and associated mortality in US adults: NHANES 1999-2018.

ABSTRACT:

Objectives

This study aimed to describe the trends of urine lead among US adults aged ≥45 years and to explore its association with all-cause and disease-specific mortality.

Methods

This study enrolled 9,669 participants from the National Health and Nutrition Examination Survey, 1999-2018. Trends in urine lead were described by logistic regression analysis using the survey cycle as a continuous variable. Cox proportional hazard regression analyses were used to quantify the association between urine lead and mortality.

Results

There was an obvious decline in urine lead concentrations from 1.203 μg/L (95% confidence interval [CI]: 1.083-1.322) in 1999-2000 to 0.478 μg/L (95% CI: 0.433-0.523) in 2017-2018, and this decline was statistically significant (P < 0.001)

SUBMITTER: Wang Q 

PROVIDER: S-EPMC11169937 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature