Identification of 3-Aryl-1-benzotriazole-1-yl-acrylonitrile as a Microtubule-Targeting Agent (MTA) in Solid Tumors.

ABSTRACT: Recently, a compound derived from recent scientific advances named 34 has emerged as the focus of this research, the aim of which is to explore its potential impact on solid tumor cell lines. Using a combination of bioinformatics and biological assays, this study conducted an in-depth investigation of the effects of 34. The results of this study have substantial implications for cancer research and treatment. 34 has shown remarkable efficacy in inhibiting the growth of several cancer cell lines, including those representing prostate carcinoma (PC3) and cervical carcinoma (HeLa). The high sensitivity of these cells, indicated by low IC₅₀ values, underscores its potential as a promising chemotherapeutic agent. In addition, 34 has revealed the ability to

SUBMITTER: Zoroddu S 

PROVIDER: S-EPMC11172098 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature