Serum proteomics of mother-infant dyads carrying HLA-conferred type 1 diabetes risk.

ABSTRACT: In-utero and dietary factors make important contributions toward health and development in early childhood. In this respect, serum proteomics of maturing infants can provide insights into studies of childhood diseases, which together with perinatal proteomes could reveal further biological perspectives. Accordingly, to determine differences between feeding groups and changes in infancy, serum proteomics analyses of mother-infant dyads with HLA-conferred susceptibility to type 1 diabetes (n = 22), weaned to either an extensively hydrolyzed or regular cow's milk formula, were made. The LC-MS/MS analyses included samples from the beginning of third trimester, the time of delivery, 3 months postpartum, cord blood, and samples from the infants at 3, 6, 9, and 12 months. Correlatio

SUBMITTER: Bhosale SD 

PROVIDER: S-EPMC11176638 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature