Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys.

ABSTRACT: Investigating the underlying factors that cause differential individual responses to chronic stress is crucial for developing personalized therapies, especially in the face of pandemics such as COVID-19. However, this question remains elusive, particularly in primates. In the present study, we aimed to address this question by utilizing monkeys as a model to examine the impacts of social rank on stress levels and physiological and behavioral responses to chronic stress primarily caused by social isolation at both the individual and group levels. Our results showed that high-ranking animals were more susceptible to chronic stress. After exposure to chronic stress, although social hierarchies remained the same, the colonies exhibited more harmonious group relationships (e.g., more prosocial

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11176666 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature