Prognostic implication of residual inflammatory trajectories in acute type I aortic dissection: dual-center prospective cohort study.

ABSTRACT:

Background

Peripheral platelet-white blood cell ratio (PWR) integrating systemic inflammatory and coagulopathic pathways is a key residual inflammatory measurement in the management of acute DeBakey type I aortic dissection (AAD); however, trajectories of PWR in AAD is poorly defined.

Methods

Two AAD cohorts were included in two cardiovascular centers (2020-2022) if patients underwent emergency total arch replacement with frozen elephant trunk implantation. PWR data were collected over time at baseline and five consecutive days after surgery. Trajectory patterns of PWR were determined using the latent class mixed modelling (LCMM). Cox regression was used to determine independent risk factors. By adding PWR Trajectory, a user-friendly nomogram was developed for predicting mor

SUBMITTER: Liu H 

PROVIDER: S-EPMC11177605 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature