Neurophysiology of Resilience in Juvenile Fibromyalgia.

ABSTRACT:

Objective

Juvenile fibromyalgia (JFM) is a chronic pain syndrome predominantly affecting adolescent girls. Resilience may be a protective factor in coping with pain, reducing affective burden, and promoting positive outlooks. Brain regions affected in JFM overlap with those linked to resilience, particularly in the default-mode network (DMN). We investigate the role of resilience on core somatic and affective symptoms in JFM and assess the neurophysiological substrates for the first time.

Methods

Forty-one girls with JFM and 40 pain-free adolescents completed a resting-state fMRI assessment and self-report questionnaires. We used clustering analyses to group JFM participants based on resilience, and principal component analyses to summarize core somatic and affective symptom

SUBMITTER: Sunol M 

PROVIDER: S-EPMC11177909 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature