School-based caries prevention using silver diamine fluoride: A pragmatic randomized trial in low-income rural children.

ABSTRACT:

Background

Dental caries is the world's most prevalent noncommunicable disease, disproportionately affecting children from low-income families and rural geographic areas.

Methods

The CariedAway 3.0 study was a cluster-randomized pragmatic non-inferiority trial comparing silver diamine fluoride (SDF) to sealants and atraumatic restorations (ART) for the prevention and control of dental caries. All participants also received fluoride varnish. Analysis consisted of mixed-effects logistic regression for caries prevalence and weighted least squares and mixed-effects negative binomial regression for caries incidence. A non-inferiority margin of 10% for the difference between groups was used. Dental caries was defined as an ICDAS score of four or greater.

Results

A total of

SUBMITTER: Ruff RR 

PROVIDER: S-EPMC11178007 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature