Trends in adverse pregnancy outcomes among women with systemic sclerosis in the United States.

ABSTRACT:

Objectives

We sought to examine temporal trends in adverse pregnancy outcomes among SSc pregnancies in a large nationwide sample.

Methods

We used the National Inpatient Sample (NIS) database from 2000 - 2017 to derive national estimates of delivery-associated hospitalizations in the United States among patients with SSc. Each SSc delivery was matched to 100 non-SSc deliveries by age, delivery year, and race. We evaluated adverse pregnancy outcomes (APOs) including maternal and fetal death, cesarean delivery, hospital length of stay, preterm delivery, intrauterine growth restriction, and hypertensive disorders of pregnancy. We used multivariable regression models with an interaction term between SSc and year and adjusting for race, advanced maternal age, diabetes mellitus, an

SUBMITTER: Kawano Y 

PROVIDER: S-EPMC11178391 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature